EXPERIMENTAL CANNABINOID 2 RECEPTOR ACTIVATION BY PHYTO-DERIVED AND SYNTHETIC CANNABINOID LIGANDS IN LPS-INDUCED INTERSTITIAL CYSTITIS IN MICE

Experimental Cannabinoid 2 Receptor Activation by Phyto-Derived and Synthetic Cannabinoid Ligands in LPS-Induced Interstitial Cystitis in Mice

Interstitial cystitis (IC) is a chronic bladder disorder with unclear etiology.The endocannabinoid system has been identified as a key regulator of immune function, with experimental evidence for the involvement of cannabinoid receptors in bladder inflammation.This study used intravital microscopy (IVM) and behavioral testing in lipopolysaccharide-

read more

Integrated physiological and transcriptomic analysis uncovers the mechanism of moderate nitrogen application on promoting the growth and (-)-borneol accumulation of Blumea balsamifera

IntroductionBlumea balsamifera, a half-woody plant belonging to the Asteraceae family, is valued as both a medicinal and industrial crop primarily for its phytochemical component, (-)-borneol.Nitrogen (N) is essential for regulating the growth of B.balsamifera and the biosynthesis of (-)-borneol; however, the molecular mechanisms by which N influen

read more


Giant Self-Kerr Nonlinearity in the Metal Nanoparticles-Graphene Nanodisks-Quantum Dots Hybrid Systems Under Low-Intensity Light Irradiance

Hybrid nanocomposites can provide a promising platform for integrated optics.Optical nonlinearity can significantly widen the range of applications of such structures.In the present paper, a theoretical investigation is carried out by solving the density matrix equations derived for a metal nanoparticles-graphene nanodisks-quantum dots hybrid syste

read more